How Does Your Clinic Use the 2-Hour Post-Spravato® Window?

If your answer involves a Spotify playlist and a dimmed room, you’re not alone… but you may be missing one of the most powerful therapeutic opportunities in mental healthcare.

Spravato® (esketamine) clinics are required to monitor patients on-site for two hours post-dose.
But monitoring isn’t engagement. And in most clinics, this neuroplastic window, rich with potential for psychological transformation, fades by without structured support.

Meet SoundSelf

A Clinical-Grade, Out-of-the-Box Solution

SoundSelf is an immersive, evidence-based digital health technology, purpose-built for use during Spravato®’s 2-hour observation period.

Patients simply wear a headset and relax into an intuitively responsive journey of vocal toning that engages breath, voice, and body in a somatic feedback process.

This activates the parasympathetic nervous system and supports deep emotional processing, therapeutic receptivity, and somatic integration.


Designed for REMS-compliant use, it transforms downtime into therapeutic engagement.

With zero extra staff, no special training, and immediate deployment, SoundSelf supports:

- Nervous system regulation

- Psychological insight and skill-building

- Consistent, measurable patient experiences

Cornerstone uses SoundSelf to improve efficacy for the most challenging cases.

“SoundSelf takes Ketamine to the next level. A lot of our patients actually have a hard time putting it into words. It’s more the expressions on their faces, the sigh of relief afterward. ”

- Jessica Shepley, Psychiatric & Family Nurse Practitioner

Why Use SoundSelf After Spravato?

❖ Maximize Neuroplasticity

Spravato opens a window of neuroplasticity. SoundSelf leverages it.

  • Deepen the emotional and cognitive impact of the medicine

  • Anchor positive change through multisensory, embodied feedback

  • Elicit valuable insights in the integration-friendly state

❖ Psychological Skills Training

Patients aren’t just sedated. They’re suggestible and receptive. SoundSelf supports:

  • Mindfulness and present-moment awareness

  • Sustained attention and absorption

  • Somatic tracking and emotional regulation

These aren’t just pleasant add-ons. They’re core to long-term outcomes and patient empowerment.

❖ Better Outcomes. Better Business.

Offering SoundSelf isn’t just clinically sound—it makes your clinic stand out:

  • Higher patient satisfaction and retention

  • More effective integration of therapeutic insights

  • Differentiation from clinics offering Spravato with Spotify or integration with coloring books.

❖ Nervous System Regulation

SoundSelf is designed to:

  • Promote parasympathetic activation (rest and digest)

  • Gently guide patients into relaxed yet alert awareness

  • Reduce anxiety and increase openness during and after sessions

Clinical Validation of SoundSelf
as a Ketamine Adjunct

Preliminary clinical findings show significant improvements in depressive symptoms in patients undergoing SoundSelf as part of post-Spravato care.

Additionally, users reported feeling more mindful and aware. These findings confirm what we have been seeing in the field: SoundSelf is a powerful tool to enhance ketamine treatment outcomes for those struggling with depression and anxiety.

SoundSelf leverages esketamine’s unique neuroplasticity window to precisely improve patient outcomes.

Stop Wasting the Medicine

Without a structured intervention during the post-dose period, patients may scroll their phones or sit in silence - wasting the powerful psychotropic effects of Spravato.

With SoundSelf, you offer a clinically aligned, scalable, and beautifully effective protocol that turns downtime into transformation.

Try SoundSelf, Risk-Free

We’re confident that once you’ve integrated SoundSelf into your practice, you’ll never look back. We also understand that integrating a new modality takes time. So we’ve made it easy for you to test SoundSelf risk-free.

With a 60-day return policy, you can take your time exploring the technology and seeing how it fits into your unique practice. If it’s not working for you in 60 days, return it for a full refund, no questions asked.

Want to learn more?

Book an exploratory 15-minute call
with Dr. Sandeep Prakash, PhD